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NexGenEsis Healthcare
NexGenEsis Healthcare franchises operate physician-supervised clinics providing non-surgical, non-opioid pain relief, injury rehabilitation, and neuropathy treatments using autologous therapies such as platelet-rich plasma, alpha 2 macroglobulin, and bone marrow aspirate injections to enhance natural healing. Some locations also offer treatments for weight loss, hair loss, and erectile dysfunction. The business model includes standard franchises, conversions for existing medical businesses, bolt-on add-ons, and area development opportunities, targeting aging adults and athletes in a competitive regenerative medicine market.
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Franchise Costs
7% royalty (greater of 7% of gross sales or $500/mo) + 1% brand fund + $300/mo technology fee
Financial Performance
Item 19 Financial Performance
Data Based On: Financial performance data is based on one franchised clinic located in Clearwater, Florida, for the 2024 calendar year.
* All figures for 'Franchised Reporting Group' are directly extracted from Table 2 for the single franchised clinic in Clearwater, Florida. EBITDA margin was calculated by dividing the EBITDA (-$49,921) by the Gross Revenue ($178,883). The best guess profit range is derived from the reported EBITDA (-$49,921) as the high end (less negative) and the Adjusted EBITDA (-$64,254) as the low end (more negative) for this single franchised unit, as Adjusted EBITDA includes additional franchise-related expenses.
Extracted Item 19 Section
Avg. Revenue: $178,883
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Unlock financial performance dataNexGenEsis Healthcare Franchise Analysis
In a market craving non-opioid alternatives to pain management, NexGenEsis Healthcare pitches autologous injections for natural healing in physician-supervised clinics. Item 19 lays bare revenue and earnings from its handful of units, while the FDD hints at hurdles like stagnant expansion and a corporate bankruptcy shadow. Does this 2022-launched brand hold regenerative potential for franchise profits, or is it still seeking its own cure?
Item 7 details a total investment of $168,250 to $362,695, kicked off by a $55,000 franchise fee, with ongoing royalties at 7% of gross sales (or minimum $500 monthly), 1% brand fund, and $300 monthly technology fee. Item 19 discloses average gross revenue of $178,883 across locations, yet EBITDA margins sit at -0% with estimated profits ranging from -$64,254 to -$49,921—signaling consistent losses that demand scrutiny for any buyer. Just 6 franchised outlets complement 8 corporate spots for 14 total, but growth stalled at 11 locations from 2023 to 2024 (+0%), underscoring a tiny footprint since franchising began in 2022 from Houston headquarters.
The system's flexibility shines with standard franchises, medical practice conversions, bolt-on add-ons, and area developments targeting aging boomers and athletes amid regenerative medicine competition. However, a disclosed bankruptcy history and negative Item 19 figures paint a high-risk picture—units aren't profitable, expansion isn't accelerating, and the parent EAD NexGenix LLC oversees a fragile network. Investors chasing healthcare upside must weigh if scaling treatments for neuropathy, weight loss, or ED can flip these reds to black, or if the model needs more time to mature.
Analysis based on the 2025 Franchise Disclosure Document. All figures should be independently verified before making investment decisions.
How NexGenEsis Healthcare Compares
| Franchise | Investment | Fee | Royalty | Locations |
|---|---|---|---|---|
NexGenEsis Healthcare Current | $168K – $363K | $55K | 7.0% | 6 |
| Gameday Men's Health | $225K – $410K | $50K | 6.0% | 257 |
| ELLIE MENTAL HEALTH | $392K – $680K | $60K | 7.5% | 255 |
| ASSISTING HANDS (UNIT) | $98K – $181K | $55K | 5.0% | 232 |
| Interim Healthcare | $156K – $239K | $75K | 5.5% | 226 |
| Vital Care | $556K – $1.0M | $60K | 19.3% | 108 |
Healthcare Services Average 24 franchises | $217K – $492K | $58K | 6.8% | – |
* Comparison based on latest FDD filings. Investment ranges from Item 7, fees from Item 5. Showing top 5 of 24 Healthcare Services franchises by location count.
Locations & Growth
Outlet Growth Over Time
Total outlets at end of each year
Geographic Distribution (2024)
Outlets by state across the United States
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Unlock location growth dataFranchisee Contacts
13 franchisee contacts on file from official FDD filings.
13 Contacts Available
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Unlock contactsDue Diligence
Litigation (Item 3)
Bankruptcy (Item 4)
Chief Development and Sales Officer Nathanael Job Millhouse filed Chapter 13 on January 6, 2017 (completed April 14, 2022, discharged May 16, 2022).
System Health (Item 20)
Franchise system changes reported in the most recent fiscal year
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Unlock due diligence reportsFrequently Asked Questions
The total initial investment to open a NexGenEsis Healthcare franchise ranges from $168,250 to $362,695. This includes a franchise fee of $55,000. Ongoing royalty fees are 7.0% of gross sales.
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